What about the FW 190? Well, it did see some regular service,though not in numbers that would compare to the Me 109 (but compared to all the other fighter types, it did rather good IIRC). And the comparison with the Spitfire, there it is important to give the Mk of the spitfire, as it saw more and major changes during the war than the 109….
Hands down the FW 190 would smash Spitfires. The FW 190 outclassed the Spitfire in area except for turning radius. However, the FW 190 met its match in the form of the P-51 and P-47. And yes, it is important to name the Mk of any plane, be it Spitfire, Me, Fw, or P.